Ụdị Chicken Sternal Collagen 2 maka ahụike nkwonkwo
| Aha ihe | Ụdị Chicken Collagen a na-adịghị ahụkebe maka ahụike nkwonkwo |
| Mmalite nke ihe onwunwe | Ụbụrụ ọkụkọ |
| Ọdịdị | Ọcha ka ọ dị ntakịrị ntụ ntụ edo edo |
| Usoro mmepụta | Usoro hydrolyzed dị ala okpomọkụ |
| Undenatured ụdị ii collagen | ：10% |
| Mkpokọta ọdịnaya protein | 60% (usoro Kjeldahl) |
| Ọdịnaya nke mmiri | ≤10% (105° maka awa 4) |
| Nnukwu njupụta | 0.5g/ml dị ka nnukwu njupụta |
| Solubility | Ezi solubility n'ime mmiri |
| Ngwa | Iji mepụta mgbakwunye nlekọta nkwonkwo |
| Ndụ shelf | Afọ 2 site na ụbọchị mmepụta |
| Nkwakọ ngwaahịa | Mbukota n'ime: Akpa PE emechiri emechi |
| Mbukota nke elu: 25kg/Drum |
Ụdị ọkụkọ na-arụsi ọrụ ike sternal Collagen Ụdị II bụ ihe na-arụ ọrụ maka ịkwado mgbanwe ahụ.Ọ na-ejikarị ụdị collagen na-abụghị denatured II nke ewepụtara site na cartilage ara ọkụkọ na obere okpomọkụ.N'ihi teknụzụ mmịpụta pụrụ iche, protein ahụ ka na-ejigide nhazi helix atọ, nke bara uru karịa n'ụzọ ndụ.
N'ime nyocha sayensị, achọpụtara na mgbe ịbanye n'ime eriri afọ, ụdị collagen Native 2 nwere ike ịmalite usoro nhụsianya pụrụ iche, nke a makwaara dị ka "oral immuno tolerance".Usoro a nwere ike ịzụ mkpụrụ ndụ na-alụso ọrịa ọgụ iji chọpụta ụmụ irighiri protein cartilage ziri ezi na anụ ahụ.N'aka nke ya, ọ na-egbochi mmeghachi omume mkpali na mwakpo mbibi, nke bụ isi ihe na-akpata nkwonkwo nkwonkwo na mgbu n'ozuzu ya, ma nwee uru nke ịkwụsị nhụjuanya nkwonkwo.
| PARAMETER | Nkọwapụta |
| Ọdịdị | White ka gbanyụọ ọcha ntụ ntụ |
| Mkpokọta Ọdịnaya Protein | 50%-70% (Ụzọ Kjeldahl) |
| Ụdị Collagen nke na-adịghị agwụ agwụ | ≥10.0% (usoro Elisa) |
| Mucopolysaccharide | Ọ dịghị ihe na-erughị 10% |
| pH | 5.5-7.5 (EP 2.2.3) |
| Mwepu na mgbanye | ≤10% (EP 2.4.14) |
| Ọnwụ na ihicha | ≤10.0% (EP2.2.32) |
| Ọla dị arọ | 20 PPM (EP2.4.8) |
| Ndu | 1.0mg/kg (EP2.4.8) |
| Mercury | 0.1mg/kg (EP2.4.8) |
| Cadmium | 1.0mg/kg (EP2.4.8) |
| Arsenic | 0.1mg/kg (EP2.4.8) |
| Ngụkọta ọnụ ọgụgụ nje bacteria | 1000cfu/g(EP.2.2.13) |
| Yist & ebu | 100cfu/g(EP.2.2.12) |
| E.Coli | Enweghị/g (EP.2.2.13) |
| Salmonella | Enweghi/25g (EP.2.2.13) |
| Staphylococcus aureus | Enweghị/g (EP.2.2.13) |
Ihe dị iche n'etiti "denatured" na "na-abụghị denatured" bụ na ozugbo a na-eme ka collagen dị elu site na oke okpomọkụ na acid, ọ na-efunahụ nhazi protein mbụ ya, nke a na-akpọ "denaturation".
N'aka nke ọzọ, ọ bụrụ na a na-amịpụta ya na obere okpomọkụ, a ga-echekwa ihe nhazi atọ-helix nke collagen, ọ ga-aghọkwa "na-enweghị ike imebi" n'ihi na nhazi protein zuru oke ma nwee ike ịnọgide na-enwe ike ijikwa ihe ndị dị ndụ. .
| Ụdị Chicken Collagen nke ala 2 | Ụdị agbapụta nke collagen ii | |
| Njirimara igodo | Collagen na-arụ ọrụ n'ụdị helix atọ mbụ | Denatured enweghị ọrụ ọ bụla |
| Usoro mmepụta ihe | Usoro mmepụta okpomọkụ dị ala iji nọgide na-enwe nhazi nke collagen | Usoro mmepụta okpomọkụ dị elu |
| Ọnụ ahịa | Elu | Ebe dị iche iche nwere ọnụ ahịa dị iche iche |
Ihe omumu sayensi gosiputara na Undenatured chicken collagen type ii na-enye abamuru maka ahu ike nkwonkwo.Nnyocha ụlọ ọgwụ na anụmanụ na-egosi na uru nke Undenatured type ii chicken collagen na-akwado na ule nke ọrịa ogbu na nkwonkwo na-akpata traumatic osteoarthritis, post-traumatic na oke ibu na-ebute ọrịa ogbu na nkwonkwo nke oke.
N'ime ule osteoarthritis nke post-traumatic, mmebi nkwonkwo mere ka mfu nke cartilage (matrix na chondrocytes) na nnukwu mbufụt mpaghara nke nkwonkwo ikpere.Mgbe ị nwetasịrị obere dose Active Collagen II, egosipụtara nke ọma uru ndị a:
1. Gbochie mmebi nke cartilage na mmanu mmanu
Ụdị collagen ọkụkọ na-adịghị ahụkebe ii nwere ike ichebe cartilage ma belata mgbanwe mmebi (normalization nke mpaghara chondroitin, ogwe anụnụ anụnụ n'akụkụ aka ekpe nke eserese dị n'okpuru ebe a), na-akpali njikọ proteoglycan na chondrocytes ma na-akwalite lubrication nkwonkwo (pasent nke chondrocytes na-arụ ọrụ na-abawanye, dị ka egosiri na ya. histogram na-acha anụnụ anụnụ n'akụkụ aka nri nke eserese dị n'okpuru).
Eserese No.1: Ụdị Chicken Collagen na-adịghị ahụkebe ii na-egbochi mmebi nke cartilage ma na-akwalite njikọ nke matrices mmanu mmanu.
1. Belata mbufụt
Ụdị collagen ọkụkọ na-adịghị ahụkebe ii na-akwalite mmetụta mgbochi mkpali nke nkwonkwo ikpere (na-ebelata ngosipụta nke ihe nrịbama mpaghara na akpụkpọ ahụ synovial, Lee histogram blue na eserese dị n'okpuru ebe a).
Eserese No.2: Undenatured chicken collagen type ii na-ebelata mbufụt nke OA.
2. Gbochie OA (Osteoarthritis)
N'ime ule osteoarthritis nke oke ibu na traumatic, mfu nke cartilage nkwonkwo ikpere (matrix na chondrocytes) na nzaghachi mkpali mpaghara na-ebute nwa oge.Obere dose
Mgbakwunye ọkụkọ collagen ụdị II nke na-adịghị agwụ agwụ nwere ike igbochi osteoarthritis n'akụkụ ndị a:
Nlele na ụmụ oke ndị buru ibu site na nri ndị nwere abụba dị elu egosila nchebe nke cartilage, mbelata mgbanwe mmebi (Cartilage zone normalization, blue histogram n'akụkụ aka ekpe nke eserese dị n'okpuru ebe a), na ịkwalite mmanye nkwonkwo site na-akpali akpali proteoglycan synthesis na chondrocytes.(Pasent nke chondrocytes na-arụ ọrụ na-abawanye, histogram na-acha anụnụ anụnụ n'akụkụ aka nri nke eserese dị n'okpuru).
Eserese Nke 3: ọkụkọ na-adịghị ahụkebe Collagen ụdị ii na-egbochi mmebi nke cartilage ma na-akwalite njikọ nke matrix na-agba mmanụ na osteoarthritis nke oke ibu kpatara.
3. Akwa bioavailability
Ọmụmụ ihe na-egosi na 1 hour mgbe ọ na-ewere Undenatured ụdị ii hydroxyproline na mouse serum na-eru a elu mkpokọta, nke na-egosi na Undenatured chicken ụdị ii nwere elu bioavailability.
Mbukota: Mbukota anyị bụ 25KG/Drum maka nnukwu iwu azụmahịa.Maka obere usoro, anyị nwere ike ịme nkwakọ ngwaahịa dị ka 1KG, 5KG, ma ọ bụ 10KG, 15KG na akpa foil Aluminom.
Amụma amụma: Anyị nwere ike inye ihe ruru gram 30 n'efu.Anyị na-ezigakarị samples site na DHL, ọ bụrụ na ị nwere akaụntụ DHL, biko jiri obiọma kesaa anyị.
Ọnụahịa: Anyị ga-ehota ọnụ ahịa dabere na nkọwapụta na ọnụọgụ dị iche iche.
Ọrụ omenala: Anyị raara onwe anyị nye otu ndị na-ere ahịa iji mesoo ajụjụ gị.Anyị na-ekwe nkwa na ị ga-enweta nzaghachi n'ime awa 24 kemgbe izipu ajụjụ.
