A pụkwara iji collagen mee ihe na nri.N'ihe dị ka narị afọ nke 12 St.Hilde-gard nke Bingen kọwara iji ofe cartilage dị ka ọgwụ na-agwọ mgbu nkwonkwo.Ruo ogologo oge, a na-ewere ngwaahịa ndị nwere collagen dị mma maka nkwonkwo.N'ihi na o nwere ụfọdụ ihe ndị ọdabara na nri: nri ọkwa na-emekarị na-acha ọcha na ọdịdị, nro na uto, ìhè na uto, mfe mgbari.Ọ nwere ike ibelata triglyceride ọbara na cholesterol, ma mụbaa ụfọdụ ihe ndị dị mkpa na-achọpụta ihe n'ime ahụ iji nọgide na-enwe ya n'ụdị kwesịrị ekwesị.Ọ bụ ezigbo nri maka ibelata lipids ọbara.Tụkwasị na nke ahụ, nchọpụta egosiwo na collagen nwere ike inye aka wepụ aluminom n'ime ahụ, belata nchịkọta aluminom n'ime ahụ, belata mmebi nke aluminom na ahụ mmadụ, ma kwalite uto mbọ na ntutu ruo n'ókè ụfọdụ.Ụdị II collagen bụ protein bụ isi na cartilage articular na ya mere ọ nwere ike ime autoantigen.Nlekọta ọnụ nwere ike ime ka mkpụrụ ndụ T na-emepụta ihe mgbochi ọrịa na igbochi ọrịa autoimmune na-ebute T cell.Collagen polypeptide bụ ngwaahịa nwere nnukwu digestibility na absorbability na molecular arọ ihe dị ka 2000 ~ 30000 mgbe collagen ma ọ bụ gelatin mebiri site protease.

Ụfọdụ àgwà nke collagen na-eme ka ọ bụrụ ihe na-arụ ọrụ na ihe oriri na-edozi ahụ n'ọtụtụ nri nwere uru ndị na-enweghị atụ na ihe ndị ọzọ: nhazi helical nke collagen macromolecules na ịdị adị nke kristal mpaghara na-eme ka ọ nwee nkwụsi ike nke okpomọkụ;Ngwunye eriri eriri eke sitere n'okike nke collagen na-eme ka ihe collagen gosipụta ike na ike siri ike, nke dabara maka nkwadebe nke ihe nkiri dị mkpa.N'ihi na agbụ molecular collagen nwere ọnụ ọgụgụ dị ukwuu nke hydrophilic dị iche iche, n'ihi ya, ọ nwere ikike siri ike ijikọ mmiri, nke na-eme ka collagen mee ihe dị ka ihe na-ejuputa na gels na nri.Collagen na-agbasawanye na mgbasa ozi acidic na alkaline, a na-etinyekwa ihe onwunwe a na usoro ọgwụgwọ maka ịkwadebe ihe ndị dabeere na collagen.

Enwere ike ịgbakwunye ntụ ntụ collagen ozugbo na ngwaahịa anụ iji metụta ịdị nro nke anụ ahụ na ọdịdị nke akwara mgbe esichara.Nnyocha e mere egosiwo na collagen dị mkpa maka imepụta anụ a na-amịghị mkpụrụ na anụ esi nri, na ka ọdịnaya nke collagen dị elu, otú ahụ ka ọdịdị anụ ahụ na-esiwanye ike.Dị ka ihe atụ, a na-eche na ọ̀tụ̀tụ̀ azụ̀ dị nro na-emetụta mbelata nke ụdị V collagen, na nbibi nke eriri collagen dị n'akụkụ nke nbibi nke njikọ peptide kpatara bụ isi ihe na-eme ka ahụ dị nro.Site n'ibibi njikọ hydrogen n'ime molekul collagen, a na-ebibi ihe owuwu nke mbụ siri ike nke superhelix, na gelatin nwere obere ụmụ irighiri ihe na ihe owuwu nke na-enweghị ike ime ka ọ dịkwuo nro nke anụ ahụ, kamakwa mee ka uru ya dịkwuo mma, mee ka ọ dị mma. àgwà, dịkwuo protein ọdịnaya, atọ ọma na oriri na-edozi.Japan ewepụtala collagen anụmanụ dị ka akụrụngwa, nke collagen hydrolytic enzymes hydrolyzed, ma mepụta condiments ọhụrụ na n'ihi, nke na-abụghị nanị nwere ụtọ pụrụ iche, kamakwa nwere ike ịgbakwunye akụkụ nke amino acids.

Na ụdị soseji dị iche iche na ngwaahịa anụ na-eme ka ọnụ ọgụgụ na-abawanye ụba, ngwaahịa mkpuchi anụ ahụ adịghị ụkọ.Ndị nchọpụta na-arụ ọrụ iji mepụta ụzọ ọzọ.Collagen casings, nke collagen na-achị, bụ n'onwe ya bara ụba na protein.Ka mmiri na mmanụ na-agbaze ma gbazee n'oge ọgwụgwọ okpomọkụ, collagen na-ebelata ihe fọrọ nke nta ka ọ bụrụ n'otu ọnụego anụ, àgwà ọ dịghị ihe nkwakọ ngwaahịa ọzọ a chọtara nwere.Tụkwasị na nke ahụ, collagen n'onwe ya nwere ọrụ nke imezi enzymes ma nwee ihe ndị na-akpata antioxidant, nke nwere ike ime ka ekpomeekpo na àgwà nri dịkwuo mma.Nchegbu nke ngwaahịa ahụ dabara na ọdịnaya nke collagen, ebe nsogbu ahụ na-agbanwe agbanwe.